Saracens fly-half Owen Farrell returns to England's starting line-up for the crunch Six Nations clash against Wales on Saturday.
Farrell was ruled out of last weekend's victory over Italy with a thigh injury but the Sarries man has recovered and replaces Toby Flood at number ten.
The Men in Black have four players selected in the starting XV with Alex Goode, Chris Ashton and Brad Barritt also selected.
Mako Vunipola starts on the bench after being replaced by Joe Marler at loose-head prop.
England: 15. Alex Goode (Saracens) 14. Chris Ashton (Saracens) 13. Manusamoa Tuilagi (Leicester Tigers) 12. Brad Barritt (Saracens) 11. Mike Brown (Harlequins) 10. Owen Farrell (Saracens) 9. Ben Youngs (Leicester Tigers) 1. Joe Marler (Harlequins) 2. Tom Youngs (Leicester Tigers) 3. Dan Cole (Leicester Tigers) 4. Joe Launchbury (London Wasps) 5. Geoff Parling (Leicester Tigers) 6. Tom Croft (Leicester Tigers) 7. Chris Robshaw (Harlequins, capt.) 8. Tom Wood (Northampton Saints)
Replacements: 16. Dylan Hartley (Northampton Saints) 17. David Wilson (Bath Rugby) 18. Mako Vunipola (Saracens) 19. Courtney Lawes (Northampton Saints) 20. James Haskell (London Wasps) 21. Danny Care (Harlequins) 22. Toby Flood (Leicester Tigers) 23. Billy Twelvetrees (Gloucester Rugby)
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